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GLP Loss
Tirzepatide, injected

Compounded Tirzepatide, Compared on What a Month Costs

Nearly every seller here charges more for tirzepatide than for semaglutide, and the size of that step varies far more than the headline prices do. From the same seller it can be nothing at all or it can double your bill, which makes the molecule decision worth more than the seller decision for most buyers.

By Hana BrennanPricing & provider data
45 providers comparedReviewed against our editorial methodologyUpdated September 2026
The shortlist

45 providers, side by side

Ordered by our published rubric — price transparency, dose-ladder pricing and access — not by price alone; the cheapest board is a separate page. Sellers that publish a price for compounded injectable tirzepatide. Brand-name figures from the same seller are excluded from the ranking rather than mixed in. A figure implausible as a standing monthly rate is kept out of the ordering and labeled on the seller's own page.

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  • Apex MD

    Published oral pricing

    Access

    From $399/mo

    Insurance

    Flat

    Visit

    All 50
  • Rivo Health

    Both molecules, both forms

    Access

    From $199/mo

    Insurance

    Flat

    Visit

    All 50
  • Aspen

    One price, either molecule

    Access

    From $179/mo

    Insurance

    Flat

    Visit

    All 50
  • CoreAge Rx

    Flat pricing on either molecule

    Access

    From $149/mo

    Insurance

    Flat

    Visit

    All 50
  • EverSlim

    A small step up to tirzepatide

    Access

    From $136/mo

    Insurance

    Flat

    Visit

    All 50
  • Rewinding RX

    Predictable monthly cost

    Access

    From $189/mo

    Insurance

    Flat

    Visit

    All 50
  • Trimi Health

    Tirzepatide without the usual premium

    Access

    From $125/mo

    Insurance

    Flat

    Visit

    All 50
  • Zera Health

    Comparing oral against injection

    Access

    From $199/mo

    Insurance

    Flat

    Visit

    All 50
  • Belle Health

    Budget semaglutide

    Access

    From $199/mo

    Insurance

    Flat

    Visit

    All 50
  • Cora Health

    Switching molecules without switching sellers

    Access

    From $135/mo

    Insurance

    Flat

    Visit

    All 50
  • Eden

    An established name

    Access

    From $298/mo

    Insurance

    Flat

    Visit

    All 50
  • Gimme Care

    Keeping both options open

    Access

    From $163/mo

    Insurance

    Flat

    Visit

    All 50
  • InstaRX

    No tirzepatide premium

    Access

    From $199/mo

    Insurance

    Flat

    Visit

    All 50
  • MyFastRx

    Low flat pricing

    Access

    From $149/mo

    Insurance

    Flat

    Visit

    All 50
  • Nouri

    Mid-market pricing

    Access

    From $225/mo

    Insurance

    Flat

    Visit

    All 50
  • Ondra Health

    Low-cost semaglutide

    Access

    From $166/mo

    Insurance

    Flat

    Visit

    All 50
  • Peak Wellness

    Flat pricing, premium tier

    Access

    From $349/mo

    Insurance

    Flat

    Visit

    All 50
  • Piper

    Straightforward flat pricing

    Access

    From $199/mo

    Insurance

    Flat

    Visit

    All 50
  • Precision Telemed

    Mid-market on both molecules

    Access

    From $199/mo

    Insurance

    Flat

    Visit

    All 50
  • Amble

    Flat semaglutide pricing

    Access

    From $289/mo

    Insurance

    Flat

    Visit

    All 50
  • Big Easy Weight Loss

    A narrow molecule gap

    Access

    From $199.67/mo

    Insurance

    Flat

    Visit

    All 50
  • bmiMD

    A narrow gap between molecules

    Access

    From $139/mo

    Insurance

    Flat

    Visit

    All 50
  • Curve

    Mid-market, flat ladder

    Access

    From $225/mo

    Insurance

    Flat

    Visit

    All 50
  • Effecty

    Flat pricing as you escalate

    Access

    From $240/mo

    Insurance

    Flat

    Visit

    All 50
  • FMmeds

    A simple two-molecule price list

    Access

    From $145/mo

    Insurance

    Flat

    Visit

    All 50
  • Get Thin MD

    Semaglutide specifically

    Access

    From $299/mo

    Insurance

    Flat

    Visit

    All 50
  • Ivy Rx

    Semaglutide at mid-market

    Access

    From $275/mo

    Insurance

    Flat

    Visit

    All 50
  • KERNX Health

    Mid-market with a flat ladder

    Access

    From $199/mo

    Insurance

    Flat

    Visit

    All 50
  • Lean Meds

    A low published entry price

    Access

    From $109/mo

    Insurance

    Flat

    Visit

    All 50
  • Longevixx

    Semaglutide, if you will not switch

    Access

    From $299/mo

    Insurance

    Flat

    Visit

    All 50
  • Maximus

    Buyers willing to commit up front

    Access

    From $359.99/mo

    Insurance

    Flat

    Visit

    All 50
  • Mondae

    Under-market on both molecules

    Access

    From $145/mo

    Insurance

    Flat

    Visit

    All 50
  • NextMeds

    A typical spread, flatly priced

    Access

    From $179/mo

    Insurance

    Flat

    Visit

    All 50
  • Pallas Health

    Wide state coverage

    Access

    From $299/mo

    Insurance

    Flat

    Visit

    All 50
  • Renlo Health

    Flat pricing above mid-market

    Access

    From $269/mo

    Insurance

    Flat

    Visit

    All 50
  • Revive Meds

    Flat ladder at a premium price

    Access

    From $459/mo

    Insurance

    Flat

    Visit

    All 50
  • Rylo Health

    Semaglutide at a flat rate

    Access

    From $249/mo

    Insurance

    Flat

    Visit

    All 50
  • The Edit

    A predictable $100 step

    Access

    From $309/mo

    Insurance

    Flat

    Visit

    All 50
  • TMates

    A narrow gap at the top end

    Access

    From $297/mo

    Insurance

    Flat

    Visit

    All 50
  • Trellis Vitality

    A modest molecule gap

    Access

    From $199/mo

    Insurance

    Flat

    Visit

    All 50
  • Tryozi

    Flat pricing, upper tier

    Access

    From $379/mo

    Insurance

    Flat

    Visit

    All 50
  • Edessa

    A realistic oral option

    Access

    From $239/mo

    Insurance

    Flat

    Visit

    All 50
  • Idgie Health

    Seeing the real oral premium

    Access

    From $179/mo

    Insurance

    Flat

    Visit

    All 50
  • TrimRx

    Reading the term before the number

    Access

    From $259/mo

    Insurance

    Flat

    Visit

  • Found

    One price for either molecule

    Access

    From $169/mo

    Insurance

    Visit

    All 50

We never show a fabricated price or rating. Facts are shown only where a provider publishes them.

How this board is built

Across the sellers that publish both figures, moving from semaglutide to tirzepatide costs a median of $64 a month more. But that median hides the useful part. Aspen and InstaRX charge the same for either molecule. Longevixx charges $149 against $299. Get Thin MD charges $169 against $299. If you already know which molecule you want, compare within it; if you might switch, the gap is the number to look at.

Some sellers list both a compounded and a brand-name price for tirzepatide. Those are different products — Zepbound dispensed as the manufacturer’s pen is not the same thing as a compounded vial — and this board ranks the compounded figure. Comparing one against the other produces a number that describes neither.

Why tirzepatide costs more, and when the gap is worth it

Tirzepatide acts on two receptors where semaglutide acts on one, and in the head-to-head trial it produced greater average weight loss. That is the clinical case for the premium. The commercial case is simpler: it is newer, in higher demand, and sellers price accordingly.

What the price difference does not tell you is which will work better for you specifically. Trial averages are averages; response varies widely, and tolerability matters as much as potency for anyone who has to stay on a drug long enough to benefit.

The practical question is whether a seller lets you switch without starting over. A seller carrying both molecules on one intake means a change of plan is a conversation rather than a new account, a new consult, and a new set of shipping delays.

How we judge sellers

  • Price transparencyCan you find what a month costs — for the molecule and the form you want — before creating an account, and does the seller's own site agree with itself?
  • Honest headlineIs the figure the seller leads with the figure it bills? A price that needs a twelve-month prepay, or that is struck through from an anchor nobody pays, is a different number from a standing monthly rate.
  • Dose-ladder pricingDoes the price hold as your dose escalates, or is it re-set at every step? This is the difference most buyers only discover in month three.
  • AccessHow many states the seller ships to, and whether it covers more than one molecule or delivery form.

We never show a fabricated price or rating, and access notes appear only where a provider publishes them. Pricing and availability change often — confirm current details on the provider’s own site.

Keep comparing

Compounded semaglutide, ranked · The lowest real monthly prices · Sellers that hold one price across doses · How we score sellers

Common questions

How much more does tirzepatide cost than semaglutide?
From the same seller, a median of about $64 a month more, across the sellers here that publish both. The range is wide: several charge identically for either molecule, while others charge roughly double. The gap is a property of the seller, not of the drugs, so it is worth comparing directly.
Is compounded tirzepatide the same as Mounjaro or Zepbound?
No. Mounjaro and Zepbound are FDA-approved products from Eli Lilly. Compounded tirzepatide is prepared by a compounding pharmacy against a prescription and is not FDA-approved or reviewed for safety, efficacy or quality before dispensing. Some sellers list both; they are different products at different prices.
Which is better for weight loss, tirzepatide or semaglutide?
In the trial that compared them directly, tirzepatide produced greater average weight loss. Averages are not predictions for an individual, and side-effect tolerance often decides which drug someone can actually stay on. That is a conversation for a prescriber rather than a table.
Does the price go up as my tirzepatide dose increases?
At many sellers, yes. Tirzepatide titrates from 2.5 mg upward, and a seller that prices per milligram will charge more at each step. Sellers that hold one figure across the whole ladder are marked on this board, and over a year that policy is usually worth more than the starting price.
Can I switch from semaglutide to tirzepatide later?
Clinically that is a prescriber's call. Commercially it is much easier at a seller that already carries both molecules, since switching does not mean a new intake, a new consult and a new account. Sellers covering both are noted in each row.