TMates review
The whole ladder, published
$249 a month for semaglutide, stepping down to $158 on a twelve-month plan — and every rung of that ladder is printed on the page.
Our verdict
The month-to-month rate is high and the disclosure is excellent, which is an unusual pairing. TMates prints all four cadences with their totals and their savings percentages, so a buyer can see exactly what a commitment buys before making one. It also charges the same for the injection and the oral, which removes a decision most sellers turn into a $50 to $100 question.
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At a glance
- Category
- GLP-1 telehealth
- Molecule
- Semaglutide · Tirzepatide
- Form
- Injection
- Dose pricing
- Flat across doses
- States
- 50
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
- Pharmacy
- Not named
- Availability
- 50 states
- Updated
- September 2026
What it is
A fifty-state telehealth service selling compounded semaglutide and tirzepatide, injectable or oral at the same price, on one-, three-, six- and twelve-month plans.
How it works
Prescription-gated telehealth with ongoing support, free shipping and cancellation stated as available at any time. Medication and support are bundled into the plan price.
Pricing transparency
Semaglutide: $249 for one month, $217 a month on three ($650 total), $175 on six ($1,050) and $158 on twelve ($1,900). Tirzepatide: $297, then $267 ($800), $217 ($1,299) and $167 ($1,999). Injectable and oral cost the same.
Branded vs compounded
Compounded semaglutide and tirzepatide, in injectable and oral preparations. Compounded drugs are not FDA-approved and are not reviewed by the FDA for safety, efficacy or quality before dispensing.
Pros and watch-outs
What we like
- Every cadence published with its total and its saving
- Oral and injectable priced identically
- Medication, support and shipping bundled
- Cancel-anytime stated
Watch-outs
- $249 month to month is toward the expensive end
- The saving only arrives with a commitment of months
- Compounding pharmacy is not named
- The twelve-month total is $1,900 in one decision
Best for
Buyers who want the full ladder visible before choosing a term.
Who should look elsewhere
Anyone whose budget is a single month at the lowest available rate.
How TMates compares
A few alternatives worth a look, depending on what you’re optimizing for.
- SkinnyRx
A tirzepatide price you can check
See SkinnyRx → - Shed
Compounded pricing without a membership
See Shed → - RxSpan MD
Comparing plan terms upfront
See RxSpan MD →
More GLP-1 telehealth sellers reviews: PollyPlexusDxPlushCarePomegranate HealthPotere Health MDPrecision Telemed
Evidence & trials · Last updated September 2026
How we assessed this. This review reflects GLP Loss’s own read of TMates’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.
Frequently asked
- What does TMates actually cost per month?
- $249 for semaglutide if you buy a month at a time. The advertised lower figures — $217, $175, $158 — each require three, six or twelve months bought upfront, and TMates publishes both the monthly equivalent and the total for each.
- Does the oral cost more than the injection at TMates?
- No. Both routes are the same price at every cadence, which is unusual — most sellers that offer both charge a premium for the tablet, and a few charge less.
- How much does a year cost?
- $1,900 for semaglutide or $1,999 for tirzepatide on the twelve-month plans, against $2,988 and $3,564 at the monthly rate. The saving is real and so is the commitment.
- Is TMates expensive?
- Month to month, yes — $249 sits toward the expensive end for compounded semaglutide. On a twelve-month plan $158 is competitive. Which of those is the honest comparison depends entirely on the term you would actually buy.
- Is TMates legit?
- TMates is a GLP-1 telehealth service. Its stated availability: 50 states. Before you pay, confirm whether it bills insurance and how its intake works in writing for your selected treatment.
- Is TMates expensive compared with other GLP-1 providers?
- TMates is listed from $249/mo in this comparison. The 387 reviewed GLP-1 providers with a listed monthly starting amount range from $76 to $1299, with a median of $179. That puts TMates above the median. The comparison excludes 192 other reviewed GLP-1 providers. Medicines, doses and payment commitments differ. Confirm the medication, renewal charge and included visits, supplies and delivery before deciding.