He & She MD review
Headlines are annual prepays
$99 a month for semaglutide means $1,188 charged today, and the oral plan renews 20% above the rate it opens at.
Our verdict
Every advertised figure here is a year paid before treatment starts. The banner reads “Injectable Semaglutide $199/month from just $99/month”, and that $99 is the annual plan: $1,188 billed upfront. Tirzepatide is built the same way at $1,908, which the site prints as $159 a month. The oral runs on a different ladder entirely — $199 a month for six months, then $1,434 per six months, or $239.
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At a glance
- Category
- GLP-1 pricing
- Molecule
- Semaglutide · Tirzepatide
- Form
- Injection · Oral
- States
- 50
- Prescription
- Required
- Compounded
- Yes — not FDA-approved
- Pharmacy
- Not named
- Availability
- 50 states
- Updated
- September 2026
What it is
A fifty-state telehealth service selling compounded semaglutide and tirzepatide by injection on annual prepaid plans, plus a compounded oral course branded GLP-1 Platinum and billed in six-month blocks.
How it works
The injectable plans are sold as a year, charged before the first shipment, and the advertised monthly figure is that total divided by twelve. The oral plan runs on six-month terms instead, with an opening block and a renewal block priced differently. What the $199 comparison figure buys, and on what term, is not spelled out.
Pricing transparency
Injectable semaglutide is an annual plan billed $1,188 upfront, advertised as $99 a month and described as a limited-time rate. Injectable tirzepatide is $1,908 upfront, printed as $159 a month. GLP-1 Platinum, the oral, is $199 a month for the first six months — a $1,194 block — and then renews at $1,434 per six months, which is $239 a month. The banner sets the $99 injectable figure against $199 a month.
Branded vs compounded
Compounded semaglutide and tirzepatide by injection, and a compounded oral GLP-1 course. Compounded drugs are not FDA-approved and are not reviewed by the FDA for safety, efficacy or quality before dispensing.
Pros and watch-outs
What we like
- Every annual total is published in dollars
- $1,188 divides to an exact $99 month
- The oral renewal rate is disclosed
- Fifty states
Watch-outs
- The $99 rate requires $1,188 at enrollment
- Tirzepatide asks $1,908 before the first dose
- The oral renews 20% above its opening rate
- Oral and injectable sit on different terms
Best for
Buyers ready to pay a full year upfront for the advertised rate.
Who should look elsewhere
Anyone who needs to pay month by month.
How He & She MD compares
A few alternatives worth a look, depending on what you’re optimizing for.
- SkinnyRx
A discounted rate, if it lasts
See SkinnyRx → - Bodybuilding Health+
A headline that is the month-to-month rate
See Bodybuilding Health+ → - Oak
Flat dose pricing without a subscription
See Oak →
More GLP-1 sellers by price reviews: Tru2uTry AgelessTryoziVirtualCare2GoWeightWatchers ClinicWholesome Clinic
Evidence & trials · Reviewed and last verified September 2026
How we assessed this. This review reflects GLP Loss’s own read of He & She MD’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.
Frequently asked
- Is He & She MD really $99 a month?
- $99 is $1,188 charged upfront for a year of injectable semaglutide. The division is exact, so the calendar-month cost is genuinely $99 — but no month exists in which a buyer hands over $99. The entire year falls due at enrollment.
- What does the tirzepatide plan cost?
- $1,908 for a year, billed upfront, advertised as $159 a month. Against the semaglutide plan that is $720 more across the year, or $60 a month, and it is due in the same single payment.
- What happens to the oral plan after six months?
- It renews at $1,434 per six months. The opening block is $199 a month, or $1,194, so the renewal costs $240 more for the same length of treatment — a step from $199 to $239 a month, which is 20%.
- Why is the oral priced differently from the injections?
- The injections are sold as a twelve-month prepay while GLP-1 Platinum is sold in six-month blocks, with a renewal rate above the opening one. He & She MD does not put the two lines on a common term, so any comparison has to be made per month.
- Is He & She MD legit?
- He & She MD is a GLP-1 sellers by price service. Its stated availability: 50 states. What our record does not establish: whether it bills insurance and how its intake works. Ask for those in writing before you pay.
- Is He & She MD expensive compared with other GLP-1 sellers by price providers?
- He & She MD publishes a starting figure of $99/mo. Across the 115 GLP-1 sellers by price providers we review that publish a single monthly figure, those run $76 to $369 with a median of $170, which puts He & She MD below the median, toward the cheaper end. The other 5 GLP-1 sellers by price providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.